Favorite  |  Set Home
Products > Others > > OTSSP167
Product name : OTSSP167
Item : CR1817
Price : 100mg, $1145; 200mg, $1885
contact : Send inquiry to: info@acesobio.com
Additional Information :  We offer significant discount for bulky quantity order,Please ask price and availability of other quantities
CAS : 1431697-89-0
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
 Name: OTSSP167 HCl salt

CAS#1431698-10-0

Chemical Formula: C25H29Cl3N4O2
Exact Mass: 522.13561
Molecular Weight: 523.88

OTSSP167 free base
Chemical Formula: C25H28Cl2N4O2
Exact Mass: 486.15893; Molecular Weight: 487.42
Elemental Analysis: C, 61.60; H, 5.79; Cl, 14.55; N, 11.49; O, 6.56


Description of OTSSP167:   OTSSP167 is a MELK selective inhibitor, exhibits a strong in vitro activity, conferring an IC50 of 0.41nM and in vivo effect on various human cancer xenograft models. Murine protein serine/threonine kinase 38 (MPK38), also known as maternal embryonic leucine zipper kinase (MELK), has been associated with various human cancers and plays an important role in the formation of cancer stem cells. MELK was also reported to be highly upregulated in multiple types of human cancer. It was implied to play indispensable roles in cancer cell survival and indicated its involvement in the maintenance of tumor-initiating cells.


Related Products :
CAY10650
CAY10650
Price: 50mg, $1045;100mg, $1785
PTC-209
PTC-209
Price: 200mg, $945; 500mg, $1485
ATB 346
ATB 346
Price: 100mg, $745; 200mg, $1185
Linezolid
Linezolid
Price: 10mg, $45; 50mg, $195; 100mg, $295; 200mg, $595
Clobenpropit (VUF 9153)
Clobenpropit (VUF 9153)
Price: 25mg, $275; 50mg, $395; 100mg, $495
Aprepitant (MK 0869)
Aprepitant (MK 0869)
Price: 10mg, $295; 50mg, $895; 100mg, $1295; 200mg, $1995
QS 11
QS 11
Price: 10mg, $95, 50mg, $375; 100mg, $655; 200mg, $1295
Bazedoxifene
Bazedoxifene
Price: 10mg, $475; 50mg, $1295; 100mg, $1995;200mg, $3295