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Product name : Rapamycin (Sirolimus)
Item : cc505
Price : 10mg, $75, 50mg, $295; 100mg, $575; 200mg, $895
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for larger quantity order
CAS : 
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Details:
Rapamycin (Sirolimus)binds the cytosolic protein FK-binding protein 12 (FKBP12) in a manner similar to tacrolimus. The sirolimus-FKBP12 complex inhibits the mammalian target of rapamycin (mTOR) pathway by directly binding the mTOR Complex1 (mTORC1). [1][2]
 
Reference:
[1] Oncology 2004, 6, 111-115.
[2] Blood 194, 183, 600-609.
 
 
Chemical Information
Molecular Weight (WM):
914.18
Formula:
C51H79NO13
CAS No:
53123-88-9
Purity:
≥ 98%
Synonyms:
Sirolimus
 
DMSO ≥ 183 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 4 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 
 

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