AT-7519 is a novel small molecule. It is a multi-cyclin-dependent kinase inhibitor with IC50 values of 210 nM, 47 nM, 360 nM, 100 nM, 13 nM and 170 nM...

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Thiazovivin

Thiazovivin is a selective, cell permeable small molecule that directly targets Rho-associated kinase (ROCK). In addition, Thiazovivin protects human ...

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Y 27632

Y-27632 is a selective Rho-associated protein kinase 1 (ROCK1, p160ROCK) inhibitor with Ki of 140 nM. Y27632, a selective ROCK inhibitor, inhibited ET...

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Nolatrexed (AG 337)

Nolatrexed (AG-337), inhibits purified recombinant human thymidylate synthase (TS) with a Ki of 11 nM, and displays non-competitive inhibition kinetic...

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Tenofovir disoproxil fumarate

Tenofovir disoproxil fumarate belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (nRTIs), which ...

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AZD 7762

AZD7762 is a novel, checkpoint kinase inhibitor with IC50 values of 5 and <10 nM for CHK1 and CHK2, respectively. AZD-7762 binds to and inhib...

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Moxifloxacin (BAY 12-8039)

Moxifloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyras...

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JNJ 7706621

JNJ-7706621 is a dual cyclin-dependent kinases and aurora kinases inhibitor with IC50 of 9 and 11 nM for CDK1/Cyclin B and aurora-A, respectively. JNJ...

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