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Product name : AZD 8055
Item : cc79
Price : 10mg, $110; 50mg, $375; 100mg, $775; 200mg, $1195
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for larger quantity order
CAS : 
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Details:
AZD 8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM. mTOR kinase inhibitor AZD8055 inhibits the serine/threonine kinase activity of mTOR, resulting in decreased expression of mRNAs necessary for cell cycle progression, which may induce cell cycle arrest and tumor cell apoptosis. mTOR phosphorylates transcription factors, such as S6K1 and 4E-BP1, which stimulate protein synthesis and regulate cell growth, proliferation, motility, and survival. [1][2]
 
Reference:
[1] Cancer Res. 2010, 70, 288-298.
[2] Cancer Res. 2012, 72, 1804-1813.
 
 
Chemical Information
Molecular Weight (WM):
465.54
Formula:
C25H31N5O4
CAS No:
1009298-09-2, 1201799-04-3 (D(-)-Tartaric Acid), 1201799-05-4 (Fumaric acid)
Purity:
≥ 98%
Synonyms:
AZD8055, AZD-8055
 
DMSO ≥ 93 mg/mL
Solubility: (R.T.: 25℃):
Water ≥ 2 mg/mL
 
Ethanol ≥ 15 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 

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