Favorite  |  Set Home
Products > PI3K/Akt/mTOR > mTOR > AZD 8055
Product name : AZD 8055
Item : cc79
Price : 200mg, $750;500mg, $1250; 1g $1950; 2g, $3050
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1009298-09-2
Molecular Weight : 465.54
Formula : C₂₅H₃₁N₅O₄
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
AZD 8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM. mTOR kinase inhibitor AZD8055 inhibits the serine/threonine kinase activity of mTOR, resulting in decreased expression of mRNAs necessary for cell cycle progression, which may induce cell cycle arrest and tumor cell apoptosis. mTOR phosphorylates transcription factors, such as S6K1 and 4E-BP1, which stimulate protein synthesis and regulate cell growth, proliferation, motility, and survival. [1][2]
 
Reference:
[1] Cancer Res. 2010, 70, 288-298.
[2] Cancer Res. 2012, 72, 1804-1813.
 
 
Chemical Information
Molecular Weight (WM):
465.54
Formula:
C25H31N5O4
CAS No:
1009298-09-2, 1201799-04-3 (D(-)-Tartaric Acid), 1201799-05-4 (Fumaric acid)
Purity:
≥ 98%
Synonyms:
AZD8055, AZD-8055
 
DMSO ≥ 93 mg/mL
Solubility: (R.T.: 25℃):
Water ≥ 2 mg/mL
 
Ethanol ≥ 15 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 

Related Products :
INK 128 (MLN 0218)
INK 128 (MLN 0218)
Price: 200mg, $950;500mg, $1695; 1g, $2490; 2g, $3590
GNE-317
GNE-317
Price: 200mg, $950;500mg, $1695; 1g, $2490; 2g, $3590
OTSSP167
OTSSP167
Price: 200mg, $950;500mg, $1695; 1g, $2490; 2g, $3590
KU 0063794
KU 0063794
Price: 200mg, $750;500mg, $1250; 1g $1950; 2g, $3050
AZD 2014
AZD 2014
Price: 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
WYE 687
WYE 687
Price: 200mg, $1750;500mg, $2690; 1g $3590; 2g, $5190
Everolimus (RAD001)
Everolimus (RAD001)
Price: 200mg, $450;500mg, $850; 1g $1250; 2g, $1850
OSI 027
OSI 027
Price: 200mg, $1250;500mg, $2150; 1g $3050; 2g, $4450