Apoptosis
Telomerase
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Product name : AZD 8055
Item : cc79
Price : 200mg, $750;500mg, $1250; 1g $1950; 2g, $3050
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1009298-09-2
Molecular Weight : 465.54
Formula : C₂₅H₃₁N₅O₄
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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AZD 8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM. mTOR kinase inhibitor AZD8055 inhibits the serine/threonine kinase activity of mTOR, resulting in decreased expression of mRNAs necessary for cell cycle progression, which may induce cell cycle arrest and tumor cell apoptosis. mTOR phosphorylates transcription factors, such as S6K1 and 4E-BP1, which stimulate protein synthesis and regulate cell growth, proliferation, motility, and survival. [1][2]
Reference:
[1] Cancer Res. 2010, 70, 288-298.
[2] Cancer Res. 2012, 72, 1804-1813.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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