Favorite  |  Set Home
Product name : MG 132
Item : cc245
Price : 10mg, $175; 50mg, $295; 100mg, $475; 200mg, $695
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
MG132 (carbobenzoxyl-leucyl-leucyl-leucinal, ZLLLal) is potent inhibitor of proteasome with IC50 of 100 nM. MG 132 potently inhibits TNF-α-induced NF-κB activation, interleukin-8 (IL-8) gene transcription, and IL-8 protein release in A549 cells by inhibition of proteasome-mediated IκBα degradation. MG-132 treatment potently induces p53-dependent apoptosis in KIM-2 cells by 26S proteasome inhibition.   [1][2]
 
Reference:
[1] J Biol. Chem. 1996, 119, 572-576.
[2] Cancer Res. 1999, 59, 5586-5595.
 
 
Chemical Information
Molecular Weight (WM):
475.62
Formula:
C26H41N3O5
CAS No:
133407-82-6
Purity:
≥ 98%
Synonyms:
MG 132
 
DMSO ≥ 95 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 95 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

Related Products :
Carfilzomib (PR 171)
Carfilzomib (PR 171)
Price: 10mg, $275; 50mg, $695; 100mg, $1295; 200mg, $1995
BMS232632 (Atazanavir, Reyataz)
BMS232632 (Atazanavir, Reyataz)
Price: 10mg, $125; 50mg, $395; 100mg, $595; 200mg, $995
Oprozomib (ONX 0912)
Oprozomib (ONX 0912)
Price: 10mg, $375; 50mg, $895; 100mg, $1295;200mg, $1995
Indinavir
Indinavir
Price: 10mg, $95, 50mg, $395; 100mg, $675; 200mg, $995
ONX 0914 (PR 957)
ONX 0914 (PR 957)
Price: 10mg, $475; 50mg, $1795; 100mg, $2795;200mg, $3795
Delanzomib (CEP 18770)
Delanzomib (CEP 18770)
Price: 10mg, $295; 50mg, $795; 100mg, $1395; 200mg, $2395
MLN-9708 (Ixazomib)
MLN-9708 (Ixazomib)
Price: 10mg, $225; 50mg, $795; 100mg, $1295; 200mg, $2195
Bortezomib (PS 341, MG 341)
Bortezomib (PS 341, MG 341)
Price: 10mg, $95, 50mg, $495, 100mg, $795; 200mg, $1175