Favorite  |  Set Home
Products > Protease > HSP > Geldanamycin
Product name : Geldanamycin
Item : cc573
Price : 10mg, $175; 50mg, $595; 100mg, $945; 200mg, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
Geldanamycin is a natural existing Hsp90 inhibitor with Kd with 1.2 μM or 0.78 μM while binding to full-length dimeric Hsp90 or the N-terminal domain Hsp90. Geldanamycin binds in the ATP-binding site in the N-terminus domain of Hsp90s (residues 1-220). Geldanamycin inhibits the ATPase activity of Hsp90 in a dose-dependent manner. Geldanamycin is a typical anti-tumor reagent, shows a mean GI50 with 0.18 μM against the panel of 60 human tumor cell lines. [1][2]
 
Reference:
[1] J Med. Chem. 1999, 42, 260-266.
[2] Cancer Chemother. Pharmacol. 1995, 36, 305-315.
 
 
Chemical Information
Molecular Weight (WM):
560.64
Formula:
C29H40N2O9
CAS No:
30562-34-6
Purity:
≥ 98%
Synonyms:
 
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

Related Products :
PF 04929113 (SNX 5422)
PF 04929113 (SNX 5422)
Price: 10mg, $295; 50mg, $895; 100mg, $1295; 200mg, $2195
KW 2478
KW 2478
Price: 10mg, $295; 50mg, $755; 100mg, $1295; 200mg, $1995
BIIB 021(CNF 2004)
BIIB 021(CNF 2004)
Price: 10mg, $165; 50mg, $675; 100mg, $1175; 200mg, $1995
SNX 2112
SNX 2112
Price: 10mg, $295; 50mg, $755; 100mg, $1295; 200mg, $1995
Tanespimycin (17-AAG, NSC330507)
Tanespimycin (17-AAG, NSC330507)
Price: 10mg, $55; 50mg, $155; 100mg, $295; 200mg, $495
NVP-AUY922 (AUY 922, VER 52296)
NVP-AUY922 (AUY 922, VER 52296)
Price: 10mg, $195; 50mg, $595; 100mg, $995; 200mg, $1695
NVP-BEP800 (VER 82576)
NVP-BEP800 (VER 82576)
Price: 10mg, $245; 50mg, $725; 100mg, $1195; 200mg, $1995
MPC 3100
MPC 3100
Price: 10mg, $295; 50mg, $795; 100mg, $1395; 200mg, $2395