Favorite  |  Set Home
Products > Protease > HSP > KW 2478
Product name : KW 2478
Item : cc326
Price : 200mg, $659;500mg, $1050; 1g $1595; 2g, $2355
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 819812-04-9
Molecular Weight : 574.66248
Formula : C30H42N2O9
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Although the mechanism of action remains to be fully elucidated, Hsp90 antagonist KW2478 appears to inhibit Hsp90, resulting in impaired signal transduction, inhibition of cell proliferation, and the induction of apoptosis in tumor cells. [1][2]
 
Reference:
[1] PCT Int. Appl. (2010), WO 2010061907 A1 20100603.
[2] PCT Int. Appl. (2010), WO 2010001989 A1 20100107.
 
 
Chemical Information
Molecular Weight (WM):
574.66
Formula:
C30H42N2O9
CAS No:
819812-04-9, 819812-18-5 (HCl)
Purity:
≥ 98%
Synonyms:
KW 2478
 
DMSO ≥ 115 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 3 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

Related Products :
MPC 3100
MPC 3100
Price: 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
BIIB 021(CNF 2004)
BIIB 021(CNF 2004)
Price: 10mg, $165; 50mg, $675; 100mg, $1175; 200mg, $1995
Geldanamycin
Geldanamycin
Price: 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
SNX 2112
SNX 2112
Price: 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
Tanespimycin (17-AAG, NSC330507)
Tanespimycin (17-AAG, NSC330507)
Price: 1g, $650;2g, $1050; 5g $1650
NVP-AUY922 (AUY 922, VER 52296)
NVP-AUY922 (AUY 922, VER 52296)
Price: 200mg, $659;500mg, $1050; 1g $1595; 2g, $2355
Ganetespib (STA 9090)
Ganetespib (STA 9090)
Price: 200mg, $950;500mg, $1695; 1g, $2490; 2g, $3590
PF 04929113 (SNX 5422)
PF 04929113 (SNX 5422)
Price: 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590