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Product name : KW 2478
Item : cc326
Price : 10mg, $295; 50mg, $755; 100mg, $1295; 200mg, $1995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Although the mechanism of action remains to be fully elucidated, Hsp90 antagonist KW2478 appears to inhibit Hsp90, resulting in impaired signal transduction, inhibition of cell proliferation, and the induction of apoptosis in tumor cells. [1][2]
 
Reference:
[1] PCT Int. Appl. (2010), WO 2010061907 A1 20100603.
[2] PCT Int. Appl. (2010), WO 2010001989 A1 20100107.
 
 
Chemical Information
Molecular Weight (WM):
574.66
Formula:
C30H42N2O9
CAS No:
819812-04-9, 819812-18-5 (HCl)
Purity:
≥ 98%
Synonyms:
KW 2478
 
DMSO ≥ 115 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 3 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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