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Product name : AMG 458
Item : cc602
Price : 10mg, $275; 50mg, $765; 100mg, $1295; 200mg, $2095
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
AMG458 is a Potent, Selective, and Orally Bioavailable c-Met Inhibitor with Ki=2.0, IC50(CT26)=120 nM significantly inhibited tumor growth in the NIH3T3/TPR-Met and U-87 MG xenograft models with no adverse effect on body weight. [1][2]
 
Reference:
[1] J Med. Chem. 2008, 51, 3688-3691.
[2] Chem. Res. Toxicol. 2008, 21, 2216-2222.
 
 
Chemical Information
Molecular Weight (WM):
539.58
Formula:
C30H29N5O5
CAS No:
913376-83-7
Purity:
≥ 98%
Synonyms:
AMG-458
 
DMSO ≥ 33 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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