Favorite  |  Set Home
Products > MAPK > p38 MAPK > TAK 715
Product name : TAK 715
Item : cc-467
Price : 200mg, $750;500mg, $1350; 1g $1950; 2g, $3150
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 303162-79-0
Molecular Weight : 399.51
Formula : C₂₄H₂₁N₃OS
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
TAK-715 is a inhibitor of p38 MAPK (IC50 = 7.1 nM for p38 MAPKα). TAK-715 also inhibits Wnt-3a-stimulated β-catenin signaling. Inhibits 22 kinases by more than 80%, including CKIδ/ε. Anti-inflammatory and anti-rheumatoid arthritis agent. Orally bioavailable. [1][2]
 
Reference:
[1] J Med. Chem. 2005, 48, 5966-5979.
[2] Chem. Biol. 2011, 18, 485-494.
                                        
Chemical Information
Molecular Weight (WM):
399.51
Formula:
C24H21N3OS
CAS No:                                           303162-79-0
 
Purity:
≥ 98%
Synonyms:
TAK-715, TAK715
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 

Related Products :
SB 203580
SB 203580
Price: 200mg, $650;500mg, $1050; 1g $1650; 2g, $2850
VX 702
VX 702
Price: 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
BMS582949 free base
BMS582949 free base
Price: 200mg, $750;500mg, $1290; 1g, $1990; 2g, $2995
LY 2228820
LY 2228820
Price: 200mg, $1750;500mg, $2350; 1g $2950; 2g, $4150
PH 797804
PH 797804
Price: 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
SB 239063
SB 239063
Price: 200mg, $1350;500mg, $1950; 1g $2650; 2g, $3750
Doramapimod (BIRB 796)
Doramapimod (BIRB 796)
Price: 200mg, $650;500mg, $1050; 1g $1650; 2g, $2850
VX 745
VX 745
Price: 200mg, $850;500mg, $1650; 1g $2250; 2g, $3450