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Product name : SB 202190
Item : cc-468
Price : 200mg, $650;500mg, $1050; 1g $1650; 2g, $2850
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 152121-30-7
Molecular Weight : 331.34
Formula : C₂₀H₁₄FN₃O
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Details:
SB 202190 is al highly selective, potent and cell-permeable inhibitor of p38 MAP kinase. Binds within the ATP pocket of the active kinase (Kd = 38 nM, as measured in recombinant human p38), and selectively inhibits the p38α and β isoforms (IC50 = 50 and 100 nM at SAPK2a/p38 and SAPK2b/p38β2 respectively). [1][2]
 
Reference:
[1] J Biol. Chem. 1996, 27, 17920-17926.
[2] Biochemistry, 1998, 37, 13846-14853.
                                        
Chemical Information
Molecular Weight (WM):
331.34
Formula:
C20H14FN3O
CAS No:
152121-30-7
Purity:
≥ 98%
Synonyms:
SB202190, SB-202190
 
DMSO ≥ 66 mg/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol ≥ 32 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 

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