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Product name : ON 01910
Item : cc628
Price : 200mg, $1250;500mg, $2090; 1g $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 592542-60-4
Molecular Weight : 473.47
Formula : C₂₁H₂₄NNaO₈S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:

ON-01910 (Estybon, Novonex, Rigosertib) is a non-ATP-competitive inhibitor to Polo-like kinase 1 (PLK1) with IC50 of 9 nM. ON01910 blocks certain proteins that are needed for cell growth and may kill cancer cells. ON 01910 is being studied in the treatment of cancer.   [1][2]

Reference:
[1] Cancer Cell 2005, 7, 275-286.
[2] J Med. Chem. 2011, 54, 6254-6276.
 
 
Chemical Information
Molecular Weight (WM):
473.47
Formula:
C21H24NNaO8S
CAS No:                                     592542-60-4
 
Purity:
≥ 98%
Synonyms:
 
 
DMSO ≥ 95 mg/mL
Solubility (25℃)
Water ≥ 95 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 

Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.

 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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