Favorite  |  Set Home
Products > Others > > CHR-6494
Product name : CHR-6494
Item : cc 691
Price : 10mg, $495; 50mg, $990; 100mg, $1795; 200mg, $2995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
 Enlarge Image                   Back
←[Previous Product]              [Next Product]→


Details:
CHR-6494 is a first-in-class Haspin inhibitor with a wide spectrum of anticancer effects. Haspin is a serine/threonine kinase that phosphorylates Thr-3 of histone H3 in mitosis that has emerged as a possible cancer therapeutic target. Recent research showed that CHR6494 reduces H3T3ph levels in a dose-dependent manner and causes a mitotic catastrophe characterized by metaphase misalignment, spindle abnormalities and centrosome amplification. [1][2]
 
Reference:
[1] J Cell Biol. 2012, 199, 251-268.
[2] Oncogene 2012, 31, 1408-1418.
 
 
Chemical Information
Molecular Weight (WM):
292.34
Formula:
C16H16N6
CAS No:
1333377-65-3
Purity:
≥ 98%
Synonyms:
 
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

Related Products :
Atglistatin
Atglistatin
Price: 200mg, $945;500mg, $1485
Ki 16425
Ki 16425
Price: 10mg, $125; 50mg, $475; 100mg, $795; 200mg, $1095
CK-636
CK-636
Price: 200mg, $845; 500mg, $1485
Y320
Y320
Price: 100mg, $845; 200mg, $1285
LRRK2-IN-1
LRRK2-IN-1
P7C3-A20
P7C3-A20
Price: 100mg, $845; 200mg, $1285
ASC-J9 (GO-Y025, Dimethylcurcumin)
ASC-J9 (GO-Y025, Dimethylcurcumin)
Price: 10mg, $175; 50mg, $595; 100mg, $945; 200mg, $1795
PF 04971729
PF 04971729
Price: 10mg, $295; 50mg, $795; 100mg, $1295; 200mg, $1995