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Pracinostat (SB 939)
Pracinostat (SB 939) is a novel potent and orally active histone deacetylase inhibitor with an IC50 of 52 nM for HDAC1 and a GI50 of 0.56 μM fo...
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AR 42 (HDAC 42)
AR 42 is a novel HDAC inhibitor with an IC50 of 0.6 μM for acute lymphoblastic leukemia (697) cell lines. AR-42 produces dose- and time-dependent a...
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Mocetinostat (MGCD 0103)
Mocetinostat (MGCD0103) is a potent HDAC inhibitor with IC50 of 15, 0.29, 1.66 μM for HDAC 1, HDAC 2 and HDAC 3, respectively. It binds to and inhi...
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Belinostat (PXD 101)
Belinostat (PXD 101) inhibits HDAC activity in HeLa cell extracts with an IC50 of 27 nM. It targets tumor cell proliferation, inducing apoptosis, prom...
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PCI 24781 (CRA 02478)
Abexinostat (PCI-24781 or CRA-024781) is novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) with potential antineopla...
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Tubastatin A hydrochloride
Tubastatin A is a potent and selective HDAC6 inhibitor. Demonstrates 1093-fold selectivity over HDAC1 (IC50 values of 15 nM for HDAC6 vs 16.4 µM...
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Panobinostat (LBH 589)
Panobinostat (LBH 589) selectively inhibits histone deacetylase (HDAC), inducing hyperacetylation of core histone proteins, which may result in modula...
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