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Products > Receptor Tyrosine Kinase > VEGFR > Cediranib (AZD-2171)
Product name : Cediranib (AZD-2171)
Item : cc438
Price : 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 288383-20-0
Molecular Weight : 450.51
Formula : C₂₅H₂₇FN₄O₃
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
Cediranib (AZD2171) is a highly potent VEGFR2 inhibitor for VEGF-stimulated proliferation and KDR phosphorylation with IC50 of 0.4 nM and 0.5 nM, respectively. AZD-2171 may prevent the growth of new blood vessels that tumors need to grow and may kill cancer cells. AZD 2171 is a type of antiangiogenesis agent and a type of vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitor. Also called AZD2171 and Recentin.  [1][2]
 
Reference:
[1] Mol. Cancer Ther. 2007, 6, 2198-2208.
[2] Clin. Cancer Res. 2007, 13, 3051-3057.
 
 
Chemical Information
Molecular Weight (WM):
450.51
Formula:
C25H27FN4O3
CAS No:
288383-20-0, 857036-77-2 (Maleic acid)
Purity:
≥ 98%
Synonyms:
AZD 2171
 
DMSO ≥ 90 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 6 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 
 

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