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Product name : CP 547632
Item : cc251
Price : 10mg, $295; 50mg, $795; 100mg, $1395; 200mg, $2395
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
CP-547632, was identified as a potent inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases  with IC50 of 11 and 9 nM, respectively. CP-547632 is selective relative to epidermal growth factor receptor, platelet-derived growth factor beta, and other related TKs. Signaling through vascular endothelial growth factor (VEGF) receptors (VEGFRs) is a key pathway initiating endothelial cell proliferation and migration resulting in angiogenesis, a requirement for human tumor growth and metastasis.  [1][2]
 
Reference:
[1] Cancer Res. 2003, 63, 7031-7039.
[2] Cancer Chemother. Pharmacol. 2007, 60, 81-89.
 
 
Chemical Information
Molecular Weight (WM):
532.40
Formula:
C20H24BrF2N5O3S
CAS No:
252003-65-9
Purity:
≥ 98%
Synonyms:
CP 547632
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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