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Product name : MLN 2238
Item : cc437
Price : 200mg, $459;500mg, $850; 1g $1195; 2g, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 1072833-77-2
Molecular Weight : 361.03
Formula : C₁₄H₁₉BCl₂N₂O₄
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
MLN-2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50 and Ki of 3.4 nM and 0.93 nM. MLN2238 has a greater overall tumor pharmacodynamic effect than Bortezomib as assessed by 20S inhibition. MLN 2238 is the biologically active form of MLN9708.  [1][2]
 
Reference:
[1] Cancer Res. 2010, 70, 1970-1980.
[2] Clin. Cancer Res. 2011, 17, 7313-7323.
 
 
Chemical Information
Molecular Weight (WM):
361.03
Formula:
C14H19BCl2N2O
CAS No:
1072833-77-2
Purity:
≥ 98%
Synonyms:
MLN 2238
 
DMSO ≥ 72 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 9 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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