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Product name : R1487
Item : cc764
Price : 10mg, $495; 50mg, $1290;100mg, $2295; 200mg, $3795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
R1487 is an orally bioavailable and highly selective inhibitor of p38α Mitogen-Activated Protein kinase. P38 mitogen activated protine (MAP) kinases form a subfamily of the well-characterized MAP kinase family of serine/threonine kinase. P38 MPA kinases are widely expressed in endothelial, immune, and inflammatory cells and play a central role in regulating the production of cytokines including TNF-α, IL-1β, and IL-6.[1]
 
Reference:
[1] J Med. Chem. 2011, 54, 2255-2265.
 
Chemical Information
Molecular Weight (WM):
424.83
Formula:
C19H19ClF2N4O3
CAS No:
449808-64-4
Purity:
≥ 98%
Synonyms:
 R-1487
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 

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