Apoptosis
MNK
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Product name : SB 239063
Item : cc-465
Price : 200mg, $1350;500mg, $1950; 1g $2650; 2g, $3750
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 193551-21-2
Molecular Weight : 368.4
Formula : C₂₀H₂₁FN₄O₂
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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SB 239063 is a potent and selective p38 MAP kinase inhibitor (IC50 = 44 nM for p38α). SB 239063 displays > 220-fold selectivity over ERK, JNK1 and other kinases; ~ 3-fold more selective than SB 203580. SB 239063 reduces inflammatory cytokine production and is neuroprotective following oral administration in vivo.[1][2]
Reference:
[1] J Pharmacol. Exp. 2000, 293, 281-288.
[2] J Pharmacol. Exp. 2001, 296, 312-321.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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