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Product name : MLN1117 (Synonyms: Serabelisib; INK1117)
Item : c2390
Price : 200mg, $1250;500mg, $2090; 1g, $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com
CAS : 1268454-23-4
Molecular Weight : 363.377
Formula : C19H17N5O3
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order.
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Details:
Description of:MLN1117 (Synonyms: Serabelisib; INK1117)
MLN1117(cas:1268454-23-4)is a selective p110α inhibitor with an IC50 of 15 nM.PI3K alpha inhibitor INK1117 selectively inhibits PI3K alpha kinase, including mutations of PIK3CA, in the PI3K/Akt/mTOR pathway, which may result in tumor cell apoptosis and growth inhibition in PI3K alpha-expressing tumor cells. By specifically targeting class I PI3K alpha, this agent may be more efficacious and less toxic than pan-PI3K inhibitors.

Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.

REFERENCES

[1]. So L, et al. Selective inhibition of phosphoinositide 3-kinase p110α preserves lymphocyte function. J Biol Chem. 2013 Feb 22;288(8):5718-31.


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