Products Category
Apoptosis
Telomerase
Contact Us
Tel: (732)236-3202
Fax: (845)673-1239
E-mail: info@acesobio.com
Add: Add: 70-9 Woodhills Dr. Goshen, NY, 10924 USA
|
Product name : MLN1117 (Synonyms: Serabelisib; INK1117)
Item : c2390
Price : 200mg, $1250;500mg, $2090; 1g, $2995; 2g, $4395
contact : Send inquiry to: info@acesobio.com
CAS : 1268454-23-4
Molecular Weight : 363.377
Formula : C19H17N5O3
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order.
 |
| Details: |
Description of:MLN1117 (Synonyms: Serabelisib; INK1117)
MLN1117(cas:1268454-23-4)is a selective p110α inhibitor with an IC50 of 15 nM.PI3K alpha inhibitor INK1117 selectively inhibits PI3K alpha kinase, including mutations of PIK3CA, in the PI3K/Akt/mTOR pathway, which may result in tumor cell apoptosis and growth inhibition in PI3K alpha-expressing tumor cells. By specifically targeting class I PI3K alpha, this agent may be more efficacious and less toxic than pan-PI3K inhibitors. Quality control data: Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS. Product will be shipped with supporting analytical data. REFERENCES[1]. So L, et al. Selective inhibition of phosphoinositide 3-kinase p110α preserves lymphocyte function. J Biol Chem. 2013 Feb 22;288(8):5718-31. |
| Related Products : |
|
|
|
|
||||||||
|
|
|
|
Chinese
Deutsch
Espanol
Francais
Italiano
Portugues
Japanese
Korean
Arabic
Russian