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Product name : TW-37
Item : cc-342
Price : 10mg, $135; 25mg, $295; 50mg, $530; 100mg, $960
contact : Send enquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for larger quantity order
CAS : 
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Details:
TW-37 is Bcl-2 inhibitor (Ki values are 0.29 μM and 1.11μM for Bcl-2 and Bcl-XL respectively). TW-37 inhibits the angiogenic potential of endothelia cells in vitro. TW-37 induces S-phase arrest and apoptosis in pancreatic cancer cell lines; also inhibits the activation of Notch-1 and Jagged-1 in vitro and vi vivo.[1][2]
 
Reference:
[1] J Med. Chem. 2006, 49, 6139-6142.
[2] Cancer Res. 2006, 66, 8698-8706.
                                           
Chemical Information
Molecular Weight (WM):
573.7
Formula:
C33H35NO6S
CAS No:
877877-35-5
Purity:
≥ 98%
Synonyms:
TW 37
 
DMSO ≥ 115 mg/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol ≥ 4 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 

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