Apoptosis
EGFR
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Product name : Ruxolitinib (INCB018424)
Item : cc189
Price : 200mg, $450;500mg, $850; 1g $1250; 2g, $1850
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 941678-49-5
Molecular Weight : 306.37
Formula : C₁₇H₁₈N₆
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Ruxolitinib (INCB018424) is an orally bioavailable JAK inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib (INCB 018424),a characterized JAK1/JAK2 inhibitor (IC50 values for JAK1, JAK2 and JAK3 are 3, 5 and 332 nM, respectively), has reached clinical trials for oncology indications, rheumatoid arthritis, and psoriasis. Ruxilitinib INCB-018424) is worth noting due to its opposite potency profile in the inhibition of the JAK enzymes when compared to CP-690,550. [1][2]
Reference:
[1] IDrugs. 2010, 13, 394-403.
[2] N. Engl. J Med. 2010, 363, 1117-1127.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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