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Product name : SU 11274
Item : cc101
Price : 200mg, $750;500mg, $1190; 1g $1890; 2g, $2995
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 658084-23-2
Molecular Weight : 568.09
Formula : C₂₈H₃₀ClN₅O₄S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
SU11274 is selective inhibitor of MET tyrosine kinase activity (IC50 = 10 nM in vitro). SU-11274 reduces cell growth in a dose-dependent manner; induces cell cycle arrest and apoptosis. SU 11274 abrogates cell motility and migration in vitro and tumor angiogenesis in vivo [1][2]
 
Reference:
[1] Cancer Res. 2003, 63, 5462-5469.
[2] Oncogene 2004, 23, 5387-5393.
 
 
Chemical Information
Molecular Weight (WM):
568.09
Formula:
C28H30ClN5O4S
CAS No:
658084-23-2
Purity:
≥ 98%
Synonyms:
PKI-SU11274
 
DMSO ≥ 92 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 2 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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