AZD 6244/Selumetinib/ARRY 142886/AZD-6244/AZD6244/ARRY-142886/606143-52-6/acesobio supply

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Products > MAPK > MEK > AZD 6244 (Selumetinib, ARRY 142886)

Product name : AZD 6244 (Selumetinib, ARRY 142886)

Item : cc-49

Price : 2g, $750;5g, $1250; 10g $1850

contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.

CAS : 606143-52-6

Molecular Weight : 606143-52-6

Formula : 457.68

Storage : at -20°C

Additional information : We offer significant discount for larger quantity order

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Details:

Selumetinib (AZD6244) is a drug being investigated for the treatment of various types of cancer, for example non-small cell lung cancer (NSCLC). Selumetinib is MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nm. ^[1][2]

Reference:

[1] Nature 2002, 417, 949-954.

[2] Nature 2006, 439, 358-362.

Chemical Information

Molecular Weight (WM):	457.68
Formula:	C₁₇H₁₅BrClFN₄O₅
CAS No:	606143-52-6, 942275-12-9 (4-methylbenzenesulfonate)
Purity:	≥ 98%
Synonyms:	ARRY 142886, Selumetinib, AZD-6244,
	DMSO ≥ 92 mg/mL
Solubility: (R.T.: 25℃):	Water < 1 mg/mL
	Ethanol < 1mg/mL
	2 years -20℃ Powder
Stability:	2 weeks -4℃ in DMSO
	6months -80℃ in DMSO