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Products > MAPK > MEK > AZD 6244 (Selumetinib, ARRY 142886)
Product name : AZD 6244 (Selumetinib, ARRY 142886)
Item : cc-49
Price : 2g, $750;5g, $1250; 10g $1850
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 606143-52-6
Molecular Weight : 606143-52-6
Formula : 457.68
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Details:
Selumetinib (AZD6244) is a drug being investigated for the treatment of various types of cancer, for example non-small cell lung cancer (NSCLC). Selumetinib is MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nm. [1][2]
 
Reference:
[1] Nature 2002, 417, 949-954.
[2] Nature 2006, 439, 358-362.
                                        
Chemical Information
Molecular Weight (WM):
457.68
Formula:
C17H15BrClFN4O5
CAS No:
606143-52-6, 942275-12-9 (4-methylbenzenesulfonate)
Purity:
≥ 98%
Synonyms:
ARRY 142886, Selumetinib, AZD-6244,
 
DMSO ≥ 92 mg/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol < 1mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
6months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 

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