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Product name : BX 795
Item : cc617
Price : 200mg, $950;500mg, $1595; 1g $2390; 2g, $3590
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 702675-74-9
Molecular Weight : 591.47
Formula : C₂₃H₂₆IN₇O₂S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Details:
BX795 is a potent and relatively specific TBK1 and IKKε inhibitor with IC50 of 6 nM and 41 nM. BX795 also suppresses MARK1, MARK2, MARK4, NUAK1, VEGFR, MLK1, MLK2, MLK3 with IC50 of 55, 53, 19, 5, 157, 50, 46 and 42 nM, respectively. BX 795 blocks TBK1- and IKKε-mediated activation of IRF3 and production of IFN-β.   [1][2]
 
Reference:
[1] J Biol. Chem. 2009, 284, 14136-14146.
[2] J Biol. Chem. 2005, 280, 19867-19874.
 
 
Chemical Information
Molecular Weight (WM):
591.47
Formula:
C23H26IN7O2S
CAS No:
702675-74-9
Purity:
≥ 98%
Synonyms:
 
 
DMSO ≥ 118 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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