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Product name : CCT 128930
Item : cc512
Price : 10mg, $245; 50mg, $825; 100mg, $1395; 200mg, $2295
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for larger quantity order
CAS : 
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Details:
CCT128930 is a novel ATP-competitive AKT inhibitor discovered using fragment- and structure-based approaches. It is a potent, advanced lead pyrrolopyrimidine compound exhibiting selectivity for AKT over PKA, achieved by targeting a single amino acid difference. CC-T128930 exhibited marked antiproliferative activity and inhibited the phosphorylation of a range of AKT substrates in multiple tumor cell lines in vitro, consistent with AKT inhibition. [1][2]
  
Reference:
[1] Mol. Cancer Res. 2011, 10, 360-371.
[2] J Med. Chem. 2008, 51, 2147-2157.
 
 
Chemical Information
Molecular Weight (WM):
341.84
Formula:
C18H20ClN5
CAS No:
885499-61-6
Purity:
≥ 98%
Synonyms:
CCT 128930
 
DMSO ≥ 68 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol ≥ 6 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 

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