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Product name : TAK 901
Item : cc-11
Price : 200mg, $1350;500mg, $1950; 1g $2650; 2g, $3750
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 934541-31-8
Molecular Weight : 504.64
Formula : C₂₈H₃₂N₄O₃S
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Details:
TAK 901 is a small-molecule inhibitor of the serine-threonine kinase Aurora B with potential antineoplastic activity. Aurora B kinase inhibitor TAK-901 binds to and inhibits the activity of Aurora B, which may result in a decrease in the proliferation of tumor cells that overexpress Aurora B. Aurora B is a positive regulator of mitosis that functions in the attachment of the mitotic spindle to the centromere; the segregation of sister chromatids to each daughter cell; and the separation of daughter cells during cytokinesis. This serine/threonine kinase may be amplified and overexpressed by a variety of cancer cell types. [1][2]
 
Reference:
[1] http://clinicaltrials.gov/ct2/show/NCT00807677.
[2] http://clinicaltrials.gov/ct2/show/NCT00935844.
 
 
Chemical Information
Molecular Weight (WM):
504.64
Formula:
C28H32N4O3S
CAS No:
934541-31-8
Purity:
≥ 98%
Synonyms:
TAK-901, TAK901
 
DMSO ≥ 101 mg/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 

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