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Product name : AS 605240
Item : cc118
Price : 200mg, $450;500mg, $850; 1g $1250; 2g, $1850
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 648450-29-7
Molecular Weight : 257.27
Formula : C₁₂H₇N₃O₂S
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Details:
AS 605204 is a potent and selective inhibitor of PI 3-kinase γ (PI 3-Kγ) (IC50 = 8 nM). It displays 30-fold selectivity over PI 3-Kδ and PI 3-Kβ and 7.5-fold selectivity over PI 3-Kα. AS-605204 suppresses the progression of joint inflammation and damage in both lymphocyte-independent and lymphocyte-dependent mouse models of rheumatoid arthritis. It is orally active and ATP-competitive. [1][2]
 
Reference:
[1] J Neuroimmunol. 2010, 222, 90-94.
[2] Curr. Med. Chem. 2009, 16, 2839-2854.
 
 
Chemical Information
Molecular Weight (WM):
257.27
Formula:
C12H7N3O2S
CAS No:
648450-29-7
Purity:
≥ 98%
Synonyms:
AS605240, AS-605240
 
DMSO ≥ 3 mg/mL
Solubility: (R.T.: 25℃):
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 
 
 

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