Apoptosis
Btk
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Product name : Pazopanib (GW786034)
Item : cc527
Price : 2g, $650;5g, $1050; 10g $1650
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 444731-52-6
Molecular Weight : 437.52
Formula : C₂₁H₂₃N₇O₂S
Storage : at -20°C
Additional information : We offer significant discount for bulky quantity order
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Pazopanib Hydrochloride (GW786034, Votrient, Armala) is a novel multitargeted inhibitor of VEGFR-1, VEGFR-2, VEGFR-3, PDGFR, FGFR, c-Kit and c-fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively. It has been approved for renal cell carcinoma and soft tissue sarcoma by the U.S. Food and Drug Administration. Pazopanib may also be active in ovarian cancer. Pazopanib also appears effective in the treatment of non-small cell lung carcinoma. [1][2]
Reference:
[1] J Clin. Oncol. 2009, 27, 3126-3132.
[2] Curr. Oncol. Rep. 2007, 9, 115-119.
Chemical Information
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
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