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Product name : Pelitinib (EKB 569)
Item : cc21
Price : 10mg, $175; 50mg, $655; 100mg, $995; 200mg, $1795
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
Additional Information : We offer significant discount for bulky quantity order
CAS : 
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Details:
Pelitinib (EKB-569) is a potent EGFR tyrosine kinase inhibitor with IC50 of 38.5 nM. EKB569 irreversibly binds covalently to epidermal growth factor receptors (EGFR) ErbB-1, -2 and -4, thereby inhibiting receptor phosphorylation and signal transduction and resulting in apoptosis and suppression of proliferation in tumor cells that overexpress these receptors. [1][2]
 
Reference:
[1] Mol. Cancer Ther. 2004, 3, 21-27.
[2] J Clin. Inverst. 2006, 116, 309-321.
 
 
Chemical Information
Molecular Weight (WM):
467.92
Formula:
C24H23ClFN5O2
CAS No:
257933-82-7
Purity:
≥ 98%
Synonyms:
EK B569
 
DMSO ≥ 13 mg/mL
Solubility (25℃)
Water < 1 mg/mL
 
Ethanol < 1 mg/mL
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.

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