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Product name : GW 5074
Item : cc-462
Price : 200mg, $650;500mg, $1050; 1g $1650; 2g, $2850
contact : Send inquiry to: info@acesobio.com,or by fax to: 1-845-673-1239.
CAS : 220904-83-6
Molecular Weight : 520.94
Formula : C₁₅H₈Br₂INO₂
Storage : at -20°C
Additional information : We offer significant discount for larger quantity order
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Details:
GW 5074 is a potent, cell-permeable, reversible, and ATP-competitive cRAF1 kinase inhibitor (IC50 = 9 nM). It shows ≥100-fold selectivity for Raf kinase versus Cdk1, Cdk2, c-Src, ERK2, MEK, p38, Tie2, VEGFR2, and c-Fms.[1][2]
 
Reference:
[1] J Neurochem. 2008, 105, 1300-1312.
[2] Bioorg. Med. Chem. Lett. 2000, 10, 223-226.
                                        
Chemical Information
Molecular Weight (WM):
520.95
Formula:
C15H8Br2INO2
CAS No:
220904-83-6
Purity:
≥ 98%
Synonyms:
GW-5074, GW5074
 
DMSO N/A
Solubility: (R.T.: 25℃):
Water N/A
 
Ethanol N/A
 
2 years     -20℃        Powder
Stability:
2 weeks     -4℃        in DMSO
 
2 months    -80℃       in DMSO
 
Quality control data:
Quality control by 1H-NMR, 13C-NMR, HPLC and LCMS.
Product will be shipped with supporting analytical data.
 
PLEASE KEEP THE PRODUCT UNDER -20℃ FOR LONG-TERM STORAGE.
 
NOT FOR HUMAN OR VETERINARY DIAGNOSTIC OR THERAPEUTIC USE.
 

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