Upadacitinib (Synonyms: ABT-494)

Description of:Upadacitinib (Synonyms: ABT-494)
Upadacitinib(CAS:1310726-60-3), also known as ABT-494, is a potent and selective JAK inhibitors...

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SMI-16a (Synonyms: PIM1/2 Kinase Inhibitor VI)

Description of:SMI-16a(cas:587852-28-6)
SMI-16a is a selective Pim kinase inhibitor with IC50 values of 0.15, 0.02 and 48 &...

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CNX-2006

Chemical Information M.Wt 545.53 Storage Please store the product under th...

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TCS PIM-1

Chemical Information M.Wt 367.2 Storage Please store the product under the...

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WHI-P154

Chemical Information M.Wt 376.2 Storage Please store the product under the...

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Oclacitinib

Chemical Information M.Wt 337.44 Storage Please store the product under th...

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Icotinib

Chemical Information M.Wt 427.88 Storage Please store the product under ...

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JAK Inhibitor I (Merck 5)

JAK Inhibitor I displays potent inhibitory activity against JAK1 (IC50 = 15 nM for murine JAK1), JAK2 (IC50 = 1 nM), JAK3 (Ki = 5 nM), and Tyk2 (IC50 ...

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SMI-4a

SIM-4a is a Pim kinase inhibitor that blocks mTORC1 activity via activation of AMPK. The serine/threonine Pim kinases have been suggested to promote t...

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Lestaurtinib

Lestaurtinib is a potent JAK2, FLT3 and TrkA inhibitor (IC50 values are 0.9, 3 and < 25 nM respectively) that prevents STAT5 phosphorylation (IC50 ...

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WP 1066

WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells. WP-1066 significantly inhibited JAK2 and its downst...

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Baricitinib (INCB028050, LY3009104)

Baricitinib, also known as INCB 028050 or LY 3009104, is an orally administered selective JAK1 andk JAK 2 inhibitor with nanomolar potency against JAK...

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Fludarabine

Fludarabine (Fludara, F-ara-A, NSC 118218) is a STAT-1 activation inhibitor and a DNA synthesis inhibitor. Fludarabine inhibits DNA synthesis by inter...

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NVP-BSK805

NVP-BSK805 is a potent and selective ATP-competitive JAK2 inhibitor with an IC50 with 0.5 nM. Within the JAK family, NVP-BSK805 displays more than 20-...

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SGI 1776

SGI-1776 is a novel ATP competitive inhibitor to Pim1, Pim2 and Pim3 with IC50 of 7 nM, 363 nM and 69 nM, respectively. Pim kinase inhibitor SGI1776 b...

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AZ 960

AZ-960 is a novel ATP competitive JAK2 inhibitor with IC50 and Ki and of <3 nM and 0.45 nM, respectively.AZ960 demonstrated selectivity for TEL-JAK...

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