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BMS582949 free base
Description of:BMS582949 free base
BMS-582949(CAS:623152-17-0) is a potent and selective P38 mitogen-activated protein kinase (P38 MAPK) inhibi...
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CGP 57380
Chemical Information
M.Wt
244.23
Storage
Please store the product under th...
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XMD17 109
Chemical Information
M.Wt
638.8
Storage
Please store the product under the...
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LGX-818
Chemical Information
M.Wt
540.01
Storage
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FR180204
Chemical Information
M.Wt
327.34
Storage
Please store the product under ...
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SB 242235
SB-242235, is a potent and selective inhibitor of p38 mitogen-activated protein (MAP) kinase. [1][2]
Reference:
[1] Arthristis Rheum. ...
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R1487
R1487 is an orally bioavailable and highly selective inhibitor of p38α Mitogen-Activated Protein kinase. P38 mitogen activated protine (MAP) kin...
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Dabrafenib (GSK 2118436)
Dabrafenib (GSK-2118436) is a potent ATP-competitive inhibitor of B-Raf, B-RafV600E and c-Raf with IC50 of 3.2 nM, 0.8 nM and 5.0 nM, respectively. Da...
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XMD 8-92
XMD 8-92 is shown to be an extremely selective ERK5/BMK1 inhibitor (KD values are 80, 190, 600 and 890 nM for BMK1, DCAMKL2, PLK4 and TNK1 respectivel...
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TAK 733
TAK-733 is a potent, selective, ATP-noncompetitive MEK allosteric site inhibitor with an IC50 of 3.2 nM. TAK733 selectively binds to and inhibits the ...
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PD 169316
PD-169316 is a potent, cell-permeable, and selective p38 MAP kinase inhibitor (IC50 = 89 nM). Inhibition of p38 MAP kinase by PD169316 blocks apoptosi...
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BIX 02189
BIX 02189 is a selective dual MEK5 and ERK5 (or BMK1) kinase inhibitor, with IC50 values of 1.5, 59, 580 and >6200 nM for MEK5, ERK5, TGFbR1 and ot...
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ZM 336372
ZM 336372 is a potent and selective c-Raf inhibitor with IC50 of 70 nM. ZM 336372 inhibits c-Raf by competing with ATP to bind to the protein. Alterna...
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PH 797804
PH-797804 is an ATP-competitive, readily reversible inhibitor of the α isoform of human p38 MAP kinase, exhibiting a Ki = 5.8 nM. PH797804 block...
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Apoptosis
MNK
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